Infectious Disease Informatics and Biosurveillance

Daniel Zeng, "Infectious Disease Informatics and Biosurveillance (Integrated Series in Information Systems)"

Publisher: Springer; 1st Edition. edition | 2010 | ISBN: 1441968911 | PDF | 488 pages | 25.3 MB

This book on Infectious Disease Informatics (IDI) and biosurveillance is intended to provide an integrated view of the current state of the art, identify technical and policy challenges and opportunities, and promote cross-disciplinary research that takes advantage of novel methodology and what we have learned from innovative applications. This book also fills a systemic gap in the literature by emphasizing informatics driven perspectives (e.g., information system design, data standards, computational aspects of biosurveillance algorithms, and system evaluation). Finally, this book attempts to reach policy makers and practitioners through the clear and effective communication of recent research findings in the context of case studies in IDI and biosurveillance, providing “hands-on” in-depth opportunities to practitioners to increase their understanding of value, applicability, and limitations of technical solutions. This book collects the state of the art research and modern perspectives of distinguished individuals and research groups on cutting-edge IDI technical and policy research and its application in biosurveillance. The contributed chapters are grouped into three units. Unit I provides an overview of recent biosurveillance research while highlighting the relevant legal and policy structures in the context of IDI and biosurveillance ongoing activities. It also identifies IDI data sources while addressing information collection, sharing, and dissemination issues as well as ethical considerations. Unit II contains survey chapters on the types of surveillance methods used to analyze IDI data in the context of public health and bioterrorism. Specific computational techniques covered include: text mining, time series analysis, multiple data streams methods, ensembles of surveillance methods, spatial analysis and visualization, social network analysis, and agent-based simulation. Unit III examines IT and decision support for public health event response and bio-defense. Practical lessons learned in developing public health and biosurveillance systems, technology adoption, and syndromic surveillance for large events are discussed. The goal of this book is to provide an understandable interdisciplinary IDI and biosurveillance reference either used as a standalone textbook or reference for students, researchers, and practitioners in public health, veterinary medicine, biostatistics, information systems, computer science, and public administration and policy.

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DENGUE

El término DENGUE fue introducido a la literatura médica como una traducción del swahili: dynga, dyenga o denga pepo que describe “un golpe súbito causado por un espiritu maligno”

Desde 1635 en America los colonizadores franceses informaron de una dolencia llamada coupe de barre. También se mencionan relatos acerca de la isla de Java en 1779 en donde se le conocía como knokkel-koorts y Filadelfia (E.U.A.) en 1780 en donde se le denominaba breakbone fever o dandy fever.

El Dengue es una enfermedad producida por cualquiera de los 4 serotipos del virus del dengue (Den-1, Den-2, Den.3 y Den-4). La presencia de los 4 diferentes serotipos en America se encuentra documentada.

1941-42. Se aisla el serotipo Den-2 en una epidemia en Pánama. En 1963 se detecto el Den-3 en Jamaica. En 1977 se aisla un nuevo serotipo en otra epidemia, este es conocido ahora como el Den-1. Finalmente en 1981 se aislo por primera vez el Den-4 en la región del Caribe.
El dengue es una enfermedad causada por un virus, transmitida de persona a persona a través de un mosquito, que es el vector de la enfermedad. En la mayoría de los casos, este es el Aedes aegypti, mosquito de hábitos domiciliarios, por lo que la enfermedad es predominantemente urbana. La susceptibilidad en humanos al virus del dengue es universal. Toda persona que es picada por un mosquito infectado puede desarrollar la enfermedad. El virus del dengue pertenece a la familia Flaviviridae y existen cuatro variantes, los serotipos 1, 2, 3 y 4. La infección con un serotipo confere inmunidad permanente contra el mismo (inmunidad homóloga) y sólo por unos meses contra los otros serotipos (inmunidad heteróloga). El dengue es un problema creciente de Salud Pública en el mundo, debido a un aumento de la población de Aedes aegypti, y a la falta de una vacuna efcaz para prevenir la enfermedad.

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Principles and Practice of Pediatric Infectious

Product Details

This comprehensive reference covers the current evaluation and management of pediatric infectious diseases. Written by recognized pediatric infectious disease specialists, 104 chapters address each infectious disease with relation to epidemiology, clinical presentation, diagnostic methods, pathogenesis, treatment and prevention. Key Topics: Current diagnostic techniques, host defenses and immune function, immunizations, hospital-acquired infections, and infections in day care environment are also discussed. Market: Pediatrics - clinical.

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RNA Viruses: Host Gene Responses to Infections

RNA Viruses: Host Gene Responses to Infections

By Decheng Yang
- Publisher: World Scientific Publishing Company

- Number Of Pages: 691

- Publication Date: 2009-05-30

- ISBN-10 / ASIN: 981283379X

- ISBN-13 / EAN: 9789812833792
Product Description:

This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; host innate and adapted immune responses to viral replication in target organs; virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and, the small interfering RNA/microRNA-mediated gene silencing pathway, a recently characterized new host defense mechanism against viral infection.Organized into 29 highly accessible and well-illustrated chapters, this volume explores state-of-the-art knowledge of the molecular mechanisms of RNA virus infection and host-virus interactions. This comprehensive compilation of the altered gene expression profiles and signal transduction pathways in host cells in response to the majority of human/animal RNA viruses opens new directions for basic and clinical research on viral pathogenesis, and also provides valuable biomarkers for researchers to select gene targets in the development of diagnostic tests and antiviral therapeutics for a number of infectious diseases.

PDF 39 MB

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